IVF Carried Out Using Frozen Embryos to Result in Live Birth

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New study reports that frozen embryos used for in vitro fertilization (IVF) have the same chance of pregnancy and child birth as compared to those who have fresh embryos implanted.

The study reports that pregnancy and live birth rates among 800 women with infertility unrelated to polycystic ovarian syndrome (PCOS) were the same as compared to women who underwent IVF using frozen embryos and those who did so using fresh embryos. Although previous studies indicate that infertile women with PCOS are more likely to have a live birth if they have frozen embryos implanted, this study suggests this is not the case for women with infertility unrelated to PCOS.

As the part of the study, women were given one cycle of IVF where either frozen or fresh embryos were implanted. In the fresh embryo group, ongoing pregnancy occurred in 35% of the women and in the frozen embryo group, ongoing pregnancy occurred in 36%. The corresponding figures for live birth rates were 32% and 34%. “Frozen embryo techniques are growing in popularity in fertility clinics worldwide. This is one of the reasons why our research is important for fertility clinicians and researchers, and of course couples who are hoping to have a child,” says lead author of the study Lan Vuong, University of Medicine and Pharmacy at Ho Chi Minh City.

Researchers explain that although many clinics are moving away from using fresh embryo transfers for IVF, the freezing process does make IVF more expensive, despite not resulting in higher rates of live births. According to In-vitro Fertilization Market report published by Coherent Market Insights, In-vitro fertilization (IVF) is the most effective form of assisted reproductive technology (ART) associated with treatment of infertility and genetic disorders related to child conception. Generally fresh embryos are used for implantation to avoid any risk related to live birth. However, this study reports that frozen embryos could also result in healthy and live birth. Vuong added that the results of the current study are specific to a common freezing method called Cryotech vitrification, so they may not apply to all current embryo freezing techniques: “Further research will be needed to compare pregnancy outcomes and live birth rates from other embryo freezing techniques.”


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