Scientists developed a capsule that helps in the easy delivery of a week’s worth HIV drugs, according to a new study published in January 2018.
Scientists from MIT and Brigham and Women’s Hospital designed a capsule that would help patients adhere to the strict schedule of dosing required for the drug cocktails used to fight viruses. `
The new capsule allows patients to take medication just once a week, however, internally providing them with medication for the entire week. This type of delivery system could be used for people at exposed to HIV, helping them prevent the infection.
“One of the main barriers to treating and preventing HIV is adherence. The ability to make doses less frequent stands to improve adherence and make a significant impact at the patient level.” says Giovanni Traverso, a gastroenterologist and biomedical engineer at Brigham and Women’s Hospital.
“We are all very excited about how this new drug-delivery system can potentially help patients with HIV/AIDS, as well as many other diseases,” Langer says, a lead author of the study.
The capsule was tested in pigs and was successfully lodged into its stomach, releasing three different HIV drugs over one week. These disintegrated into smaller components that passed through the digestive tract.