Organ preservation involves removal of organs from the bodies, which are then stored for transplantation. Organ preservation systems are exclusively prepared and maintained according to the biological environment (temperature and oxygen) needed to store particular organs. Different body organs require specific and suitable storage conditions to maintain their anatomical and physiological processes. Important parameters in organ preservation include delivering of high quality organs to the donors, matching the patient and organ suitability, and restart of life of the organs and sustaining functions after the transplantation. Organ transplantation process starts with removing the needed organ from the donor body, then the organ is stored and transported. The conditions of the organs are maintained in its natural state and functioning by avoiding any significant damage. Organ is preserved thoroughly till it is transplanted into the patient’s body. The most suitable temperature for preservation is between 4°C to 8°C, which significantly reduces the metabolic rate of the organ.
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Organ transplantation procedure has evolved with increased procedural feasibility and better understanding of immunity system and reasons behind organ rejection has allowed for improved matching rates for organs and patients after transplants. Enhancement in surgical techniques along with networking of organ donor has saved many lives, owing to improvement of transplantation procedures.
Increasing demand for organ transplants is expected to fuel growth of organ preservation market
According to Organ Procurement and Transplantation Network (OPTN), in 2017, over 117,000 people are in the waiting list of national organ transplant and only around 17,155 organs are transplanted in the year.
Moreover, according to National Kidney Foundation, in 2016, around 121,678 people are waiting for lifesaving organ transplants in the U.S., among which, around 100,791 people are waiting for kidney transplants.
Moreover, many innovative techniques are promising such as normo, sub-normo and hypothermic perfusion technologies, hypothermic surgery and gas persufflation. Furthermore, potential organ preservation techniques such as Organ Bioengineering and Organ Banking are unique and scalable opportunities.
Significant gap between supply and demand and low donation rates are the factors restraining growth of the market.
Advancement in technology and enhancement in techniques are expected to fuel growth of the organ preservation market
Tissue preservation is getting easier due to rapid advancement in technology and can greatly effect by improved matching of donor organ and receiver with reduced organ rejection rates, limiting organ discard, increasing donor utilization, reducing costs such associated with short-notice plane and helicopter transportation. Adult-derived stem cells such as mesenchymal stem cells (MSCs) offer great therapeutic promise for numerous clinical applications. MSCs can be taken from any tissue in the body that is capable of healing bone marrow, dental pulp, blood, adipose, liver, brain, pancreas, and placenta.
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Regional growth engines of organ preservation market
Regional segmentation of the organ preservation market by Coherent Market Insights comprises, North America, Europe, Latin America, Asia Pacific, Middle East, and Africa. North America market is expected to hold a dominant position in the global organ preservation market. This is mainly due of better organ preservation facilities, research and development, and skilled professionals in the region. Moreover, increasing geriatric population, as they are more prone to chronic diseases, further augments growth of the market. Asia Pacific region is expected to witness highest growth rate in the market, owing to increasing customer base, increasing organ donation awareness, and increasing healthcare expenditure. Furthermore, low cost and availability of technology, increasing transplant surgeries, and increasing organ donation awareness are the few factors fueling growth of the market in the region. For instance, around 220,000 people had shown interest in post-mortem organ donation, according to a registry held by China Organ Transplant Development Foundation (COTDF), in 2016, owing to various awareness programs held by the organization. Indian government has initiated an organ donation awareness programs such as Organ Donation Day and National Organ & Tissue Transplant Organization (NOTTO), owing to wide adoption of organ donation activities in India.
Key players in the organ preservation market
Key players operating in the global organ preservation market include Teva Pharmaceutical Industries Ltd., Dr. Franz Köhler Chemie GmbH, BioLife Solutions, XVIVO Perfusion AB, Bristol-Myers Squibb, Inc., and ToleroTech, Inc., Lifeline Scientific, Preservation Solutions Inc., and Claris Injectables Limited. Moreover, in 2015, Dr. Franz Köhler Chemie GmbH, opened a new manufacturing site for Custodiol, the market leading organ protective solution of the company.