Researchers Develop New Treatment for Allergic Contact Dermatitis

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A new treatment for allergic contact dermatitis has been found by the researchers, according to a study conducted on March 8, 2018.

A mixture of antioxidants and moisturizers were developed by the researchers who were working on an experimental model of allergic contact dermatitis (ACD). The inflammatory response to the irritant were suppressed by these antioxidants and moisturizers. It gave relief from itching, swelling was reduced, and peripheral nerves in the affected areas were protected. Exposure to an allergen causes allergic contact dermatitis. Perfumes, soaps or organic compound are some of the sensitizing allergens. Although symptoms can be reduced, few weeks are required to recover from this.

One of the current treatments available for allergic contact dermatitis is by using corticosteroids. It causes skin atrophy, spider veins, loss of skin color, and can even increase the risk of cancer. The barrier of skin can be disrupted by these corticosteroids leading to adrenal suppression, insulin resistance, hypertension, and cataract. On the other hand, the new cream that has been developed was successful in treating allergic contact dermatitis in mice. Also, it did not have any side effects of corticosteroids.

Nicolas Bazan, professor said, “While our results are very promising, additional studies are needed to determine the ideal duration of treatment and the most efficacious concentrations of the active components in the test formulations that will best alleviate ACD.” Most of his studies are focused on responses to damage to the brain and retina.


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