Researchers have developed a new biosensing material for counting dividing cells and detecting biomolecules, according to a study conducted on February 26, 2018.
A nanoplasmonic material is used to make the slide. Absorption and scattering of light by plasmonic materials happens in interesting ways and this gives unique sensing properties to them. These materials are highly preferred by biologists and chemists as they can be used in many fields such as biosensing and solar cells.
A new biosensor has been developed by the research team and a nanoplasmonic material has been used to make it. A large number of cells can be accommodated on a single substrate using this material and cell proliferation can also be monitored. This material is highly sensitive and using this, the cells were found to survive for over seven days.
This material, which looks like a piece of glass, is coated in tiny nanoplasmonic mushroom-like structures known as nanomushrooms, with stems of silicon dioxide and caps of gold. A biosensor is formed by all these together and interactions at molecular level can be detected by these biosensors. When the biosensor works, nanomushroom caps are used as optical antennae. The properties of the slide changes when light is absorbed and scattered by the nanomushrooms. Size, shape and material of the nanomaterial determines the absorbance and scattering of light. Unlike earlier, cells can be counted directly by the nanomushrooms.
Nanomushroom biosensors can be fabricated by developing a new method. Since uniformity across the material surface cannot be assured, large-scale production of nanoplasmonic materials is still a challenge. Therefore, there is a lack of biosensors for clinical examinations. As a solution to this problem, a novel printing technique was developed. Ranging from electronics to medicine, these sensors can be used in various fields.
This development of biosensors, which will be able to monitor cell proliferation, will increase the growth of global cell culture market, as detailed in the global cell culture market report published by Coherent Market Insights.